Cancer of the Stomach – USMLE exams

by / Tuesday, 03 August 2010 / Published in Surgery

Cancer of the Stomach

  • Most cancers of the stomach are found to be malignant
  • There is a link of stomach cancers to blood group A, which may indicate a genetic predisposition to the condition
  • Linitis plastica is a diffuse cancer that is fatal within months, and is the most deadly form of gastric cancer

Signs and Symptoms for all:

  • GI discomfort and/or pain
  • Weight loss
  • Anemia
  • Anorexia

There is an increased risk when there is:

  • Low fiber consumption
  • Excess nitrosamines in the diet (due to smoked meats)
  • Excess salt intake in the diet
  • Chronic gastritis

There are some classic findings in metastatic gastric cancer, they include:

Virchow’s node:

  • Left supraclavicular node is hard

Krukenberg Tumor:

  • The metastasis of gastric cancer bilaterally to the ovaries
  • Ovaries are palpable in this case
  • They are signet-ring cells

Sister Mary Joseph sign:

  • Hard nodule at the umbilicus due to metastasis
  • Indicative of a very poor prognosis


  • Surgery + chemotherapy
  • Palliative care is often the only choice if too advanced

2 Responses to “Cancer of the Stomach – USMLE exams”

  1. This is an excellent high yield information that is just what’s needed to know for the USMLE Exam.
    Thanks for the nice blog

Leave a Reply