Cancers of the Lung

by / Monday, 06 September 2010 / Published in Pathology

CANCER OF THE LUNG

CENTRALLY ARISING PERIPHERALLY ARISING
Small Cell Carcinoma – linked to smoking, can produce ACTH and ADH, may be linked to Lambert-Eaton syndrome

Squamous Cell Carcinoma – linked to smoking and the production of ectopic  PTrP.

Adenocarcinoma – is the most common peripherally arising cancer of the lung.

Large Cell Carcinoma – is an undifferentiated carcinoma of the lung.

Bronchioalveolar Carcinoma – this is the lung cancer that is not thought to be related to smoking

Lung cancer can cause a wide array of symptoms (aside from cough, hemoptysis, wheezing, bronchial obstruction).  The most common symptoms that can arise from lung cancer are:

–       Pancoast’s tumor (a carcinoma that originates in the apex of the lung and can compress the cervical sympathetic plexus, resulting in Horner’s syndrome)

–       Superior vena cava syndrome

–       Horner’s syndrome (Ptosis, Anhydrosis, Miosis)

–       Paraneoplastic disorders (PTrP, ADH, ACTH)

–       Recurrent laryngeal nerve symptoms (hoarseness)

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