Types of Renal Tubular Acidosis
Renal Tubular Acidosis:
|Type I||A defect of the distal tubule (H+ gradient)||>5.5|
|Type II||Proximal tubule fails to resorb HCO3||>5.5 early then <5.5 as the acidosis worsens|
|Type IV||Decr Aldosterone (leading to hyper K+ and hyper Cl-
From decr secretion seen in DM, interstitial nephritis, ACEI’s, heparin, and NSAID use.
May also be due to aldosterone resistance from sickle cell or urinary obstruction